| Location | | Predicted Line |
| |
| at | Buffalo Bills
| | Buffalo Bills
| 21
| | Cleveland Browns
| 16
| -5
|
| |
| Neutral | | | Buffalo Bills
| 20
| | Cleveland Browns
| 17
| -3
|
| |
| at | Cleveland Browns
| | Cleveland Browns
| 19
| | Buffalo Bills
| 18
| -1
|
| | Cleveland Browns
| | Buffalo Bills
| |
| |
| | Stats | | Stats | |
| |
| | Comp | Att | Yds | Td | Int | QB Rating | | | Comp | Att | Yds | Td | Int | QB Rating |
| QB | Brady Quinn
| 17
| 32
| 168
| 1.04
| 1.6
| 58.22
| QB | Trent Edwards
| 18
| 31
| 211
| 1.91
| 0.95
| 86.63
|
| |
| | Yds | Td | | Yds | Td |   |
| RB | Jamal Lewis
| 65
| 0.0
| | RB | Fred Jackson
| 71
| 0.0
| |
| RB | Jerome Harrison
| 38
| 0.0
| | RB | Marshawn Lynch
| 38
| 0.55
| |
| RB | Josh Cribbs
| 28
| 0.0
| | RB | Trent Edwards
| 17
| 0.0
| |
| |
| | Yds | Td | | Yds | Td |   |
| WR | Mohamed Massaquoi
| 58
| 0.15
| | WR | Terrell Owens
| 69
| 0.35
| |
| WR | Mike Furrey
| 23
| 0.0
| | WR | Lee Evans
| 51
| 0.87
| |
| WR | Josh Cribbs
| 21
| 0.0
| | WR | Fred Jackson
| 31
| 0.17
| |
| WR | Jerome Harrison
| 17
| 0.0
| | WR | Josh Reed
| 31
| 0.17
| |
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